Aiguo Shen completed his undergraduate work at Hubei University in Wuhan (2001) with a major in Chemistry and a minor in higher Pedagogical Education. Aiguo’s doctoral work was done at Wuhan University in Wuhan (2006) under the direction of Prof. Dr. Jiming Hu. He then worked as a lecturer at College of Chemistry and Molecular Sciences, Wuhan University and got associate professorship in 2008. Aiguo performed postdoctoral research in the laboratory of Alfred J. Meixner at the Tubingen University, Germany (2012). His efforts in Meixner lab focused on applying tip-enhanced Raman spectroscopy (TERS) to probe the surface of biofilms and cells. In 2016, he has been promoted to a full professor of Analytical Chemistry at Wuhan University. His research activities involve tissue and cell characterization, nanoparticle synthesis, self-assembly, nanofabrication, nano-bioanalysis and instrument development, including over 70 papers published in Advanced Functional Materials, Analytical Chemistry, Scientific Reports, ACS Applied Materials & Interfaces, Journal of Materials Chemistry, Chemical Communications and Biosensors & Bioelectronics. In particular, he utilized molecular-specific surface-enhanced Raman spectroscopy (SERS) to perform study on the fundamentals and applications of rapid sensing, separation-free detection and point-of-care diagnosis, also recently on exploring the feasibility of biomedical imaging within nanometer range of spatial resolution even by means of routine confocal Raman microscopy.