Valentin A. Bobrin and Michael J. Monteiro*


Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland 4072, Australia


Building nanostructures with controlled geometry and multiple compartments with a variety of chemical functionalities represent an important development in the design of nano- objects.12 Multicompartment tadpole nano-objects are a rare and intriguing class of structures with potential in a wide range of applications. Here, we demonstrate the synthesis of chemically multifunctional tadpoles made at high weight fraction of polymer (> 10 wt. %). The tadpoles are synthesized using two different thermoresponsive MacroCTAs with either alkyne or pyridyldisulfide end-groups, allowing chemical functionality in the head, tail, or both. Water-soluble molecules or polymers were coupled to either the head, tail, or both without a change in tadpole configuration. In addition, the tadpoles can be dried, rehydrated, and stored in water for 5 months without a change in shape. This method represents a new and an important synthetic development in the design of nano-objects.3



  1. Moughton, A.O., Hillmayer, M.A., Lodge, T.P., Macromolecules, 2012, 45, 2.
  2. Groschel, A.H., Muller, A.H.E., Nanoscale, 2015, 7, 11841.
  3. Bobrin, V.A., Monteiro, M.J., J. Am. Chem. Soc., 2015, 137, 15652.


Valentin A. Bobrin

Title: Mr.

Australian Institute for Bioengineering and Nanotechnology (AIBN), University of Queensland, Australia

Phone: 0733464162 Fax: 0733463973 E-mail:

Research interests: ‘Living’ radical polymerization, ‘Click’ chemistry, Self-Assembly, Nanomaterials, Material characterization.


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