Next Generation Biomanufacturing and Commercialization of Novel Modalities

Munro, Trent

One Amgen Center Drive,
Amgen Inc.
Thousand Oaks, CA, USA

The field of Biotechnology has seen expansion in number and complexity of modalities which are being commercialized.  In this presentation I will cover case studies of two recent Amgen programs outlining challenges of commercial development of an engineered bispecific antibody and a live oncolytic virus.  This focus of the presentation will be around manufacturability and CMC related issues. In addition I will cover some recent advances Amgen has made in the technology used for Biologic manufacturing platforms in general.